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Comparative regimens included percutaneous administration of autologous bone marrow locally (2 ml, postoperative day 7) as well as an autologous cortical graft inserted in the bone defect immediately after its formation

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During host cell infection, CoVs trigger an imbalance involving increased ROS production and reduced antioxidant host responses, thereby leading to increased redox stress, reduced antiviral host responses, and increased virus-induced inflammation and apoptosis, ultimately causing cell and tissue damage and end-organ disease 3