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Another RCT showed a significant difference in hunger, fullness and food preoccupation up until week 24 between liraglutide + IBT and placebo + IBT: these differences were not maintained at week 52, despite the greater weight loss in the liraglutide-treated participants [68]

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Despite its advantages, GST is a dimeric enzyme, and its crystal structure reveals four exposed cysteine residues that can be easily oxidized to form aggregates 20