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GSH and Fer-1 inhibited testis ferroptosis of older S8/ Gss −/− mice We further examined the effects of GSH and Fer-1 on testis ferroptosis

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As the completed molecule, GSH serves directly as a substrate and cofactor for multiple glutathione-dependent enzyme systems, making it a valuable research tool for investigating redox chemistry, thiol-disulfide exchange processes, enzyme-cofactor interactions, and glutathione-associated regulatory mechanisms