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[4] The regulation of levels of ROS, levels of oxidized and reduced glutathione and other thiols, and antioxidant enzymes (such as GSTs and glutathione reductase) are important in determination of the most stable conditions for redox control, or for activation of apoptosis

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Warnings: IV glutathione for skin whitening has been associated with renal toxicity, Stevens-Johnson syndrome, and neurological effects in case reports and prompted a Philippines FDA advisory

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