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In an LPS-induced atherosclerosis mouse model, PYC pretreatment significantly inhibited TLR4 expression and NF-κB activation, resulting in a decrease in the number of macrophages accumulating in plaques and a reduction in the levels of pro-inflammatory cytokines (Luo et al., 2015)

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Types:Single

Most GI side effects peak between weeks four and eight and resolve by week twelve for the majority of users