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Inflammation – haptocorrin levels can increase due to granulocyte activation or as an acute phase response Decreased clearance: Renal failure – decreased clearance of transcobalamin–B12 complexes Mechanism: Most elevated B12 is not free or biologically active , but rather bound to haptocorrin , which has a long half-life and is increased in certain diseases

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Why Saline Solution is Preferred for Nasal Sprays When researching peptide reconstitution, you will often read that bacteriostatic water is the standard diluent