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Proposed mechanisms of AOD-9604: Stimulates lipolysis (fat breakdown) Increases fat oxidation Promotes mobilization of stored fat Influences lipid metabolism Importantly, AOD-9604 does not appear to significantly increase growth hormone levels, IGF-1 levels, water retention, or organ growth

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there were no fatal events and no consistent dose pattern 3 In TRANSCEND-T2D-1, serious adverse events occurred in 4%, 1% and 4% of participants in the Retatrutide groups, versus 1% with placebo