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longa polyphenols are part of the group of selected phytochemicals studied as a complementary therapy for IBD in randomized clinical trials (Sugimoto et al., 2020

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For example, alcohol causes the malfunctioning of biological signalling molecules by increasing the amount of ROS, while decreasing the levels of cellular antioxidants (267), leading to the accumulation of acetaldehyde (268) and causing cell apoptosis as a result of it inducing mitochondrial dysfunction (269)