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IR induced metabolic disturbances lead to degradation of brain function, and prolonged uncontrolled high blood glucose levels adversely affect a variety of metabolic pathways such as oxidative stress, formation of advanced glycosylation end products (AGEs), and protein kinase C activation, while metabolic disturbances inducing cerebral microvascular damage affect the extent of cognitive impairment (1, 7)
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When these symptoms appear, you may find yourself not being able to function at your best
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